The Mantoux test is a qualitative, skin test to screen in vivo sensitization by Mycobacterium tuberculosis either due to active infection or past infection. It is also used to check the prophylaxis and efficacy of […]
The Roundworm, Ascaris lumbricoides is the largest nematode parasite in human intestine. Disease caused by A. lumbricoides is called Ascariasis. Laboratory diagnosis of ascariasis can be made by demonstration of parasite (eggs, larvae or adult […]
Glycolysis is the major pathway for the utilization of glucose in the body. Glycolysis is defined as the sequence of reactions for the breakdown of Glucose (6-carbon molecule) to two molecules of pyruvic acid (3-carbon […]
Anemia is the condition of decrease in number of circulating red blood cells (and hence hemoglobin) below a normal range for age and sex of the individual, resulting in decreased oxygen supply to tissues. Iron […]
Sudan Black B (SBB) is a fat soluble dye which has very high affinity for neutral fats and lipids. SBB staining is useful for for the differentiation of Acute myeloid leukemia (AML) from Acute lymphoid […]
Coagulase is an enzyme that works in conjugation with normal plasma components to convert fibrinogen to finbrin and causes clotting of plasma. This enzyme is a good indicator of pathogenic potential of Staphylococcus aureus. As […]
Genus Entamoeba includes a group of amoebic parasites. Among them Entamoeba histolytica is an important human pathogen causing amoebic dysentery as well as hepatic amoebiasis. Entamoeba coli is a commensal of large intestine, but doesn’t […]
Myeloperoxidase is a lysosomal enzyme present in the primary azurophilic granules of neutrophils, eosinophils and to a certain extent, monocytes. Lymphocytes do not contain myeloperoxidase. Purpose of Myeloperoxidase stain Myeloperoxidase (MPO) stain is useful for […]
Reticulocytes are immature red blood cells (RBCs) with considerable quantities of ribosomal and mitochondrial RNA. Normally, there are a small number of reticulocytes in the peripheral blood which remain for 24-48 hours during maturation. Reticulocyte […]
Hematoxylin and Eosin (H&E) staining is the most widely used staining technique in histopathology. As its name suggests, H&E stain makes use of a combination of two dyes, namely hematoxylin and eosin. This combination deferentially […]
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